General Troubleshooting Steps
Install Microsoft Visual C++ Redistributable - Try installing Microsoft Visual C++ Redistributable for Visual Studio 2015 to see if that helps resolve the issue. The download for that can be found here: https://www.microsoft.com/en-ca/download/details.aspx?id=48145
Download and install the latest Windows Updates - Ensure that your Windows OS has been updated to the latest version via Windows Update. Most issues with crashes, errors, or with Visual VC++ (and various software) generally are due to out-of-date Windows OS patches or service packs.
Check your drivers - Outdated drivers are one of the first things to check when any software is having problems. Make sure that all of your drivers are updated.
Check you system specs - Make sure your system meets Oxygen Not Included's system requirements. If it does not, you are still welcome to file a report; just make sure to let us know what the the computer specs are.
Security software - Unfortunately malware, firewall and virus protection programs can be a bit unpredictable at times. Try disabling anything you have running then try running the game again.
3rd-Party Software - Pop-up blockers, ad-blockers, and other types of software running in the background can sometimes cause problems. Turn off anything you have running in the background then try running the game again.
Often, the problems that users are experiencing are a result of local game files being corrupted, or incompletely downloaded. These problems include missing textures or effects, or crashing when loading specific areas or items, while the game generally runs fine.
Verify your game cache integrity on Steam - Verifying the integrity of your game cache ensures that there are no game files missing and corrupted files are replaced.
- Right-click Oxygen Not Included. in your Steam Library > "Properties"
- Select the "Local Files" tab;
- Click the "Verify Integrity of Game Cache" button
- When the process is complete, launch Oxygen Not Included
Ensure that your system is running the game with a a dedicated GPU (Not Integrated)
Some laptops with NVIDIA or AMD graphics cards actually contain two graphics chips; an Intel integrated chip for power-saving and a dedicated NVIDIA or AMD chip for high-performance uses such as gaming. Your graphics driver will detect which chip to use based on the program that you're running, but may not correctly detect that the high performance chip is required to run Oxygen Not Included.
You will have to go into your AMD (CCC Control Panel) or NVIDIA Control Panel and force your dedicated GPU to launch and run Oxygen Not Included. instead of your integrated Intel card.